ABSTRACT
Reaction of S-cyano-6-aryl-2-thiouracil 1A-C or its methylthio derivatives 2A-C with hydrazonoyl chlorides 3a-h led to the formation of 7-atyl-6-cyano-1, 2, 4-triazolo [4, 3-alpha] pyrimidin-5 [1H]-one derivatives 8. The mechanism and the regioselectivity of the studied reactions were discussed with the help of the given X-ray crystallographic data
Subject(s)
Uracil/analogs & derivatives , HydrazinesABSTRACT
Irradiation of 2-phenyl-5-[2-thienyi]-tetrazole 1 with acrylate derivatives 2A-E [molar ratio 1:1] in anhydrous benzene gave the corresponding title compounds 1-phenyl-3-[2-thienyl]-pyrazoline derivatives 4A-E as end products. The mechanism and the regiochemistry of the studied reactions are discussed
Subject(s)
Pyrazoles/chemistry , Anti-Infective AgentsABSTRACT
Pyridazine derivatives are known to exhibit antiallergic, antihypertensive as well as plant growth regulating effects. In continuation to our previous study in this field we here report the isolation of 4,5-dihydro6-[2,4-dimethyl phenyl]-3-[2H] pyridazinone azine [II a] from the reaction of 6-[2,4-dimethyl phenyl] 4,5-dihydro-pyridazin-3-one [I a] with hydrazine hydrate